• Diabetes drug shows promise in treatment of neurodegenerative disease
    Researchers have found that a drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death. They believe that their findings may be relevant to other neurodegenerative diseases.  A Phase II trial will be starting shortly. 
  • Parkinson's disease-like sleep and motor problems observed in alpha-synuclein mutant mice
    In the quest for an animal model of Parkinson’s disease that mimics motor and non-motor symptoms of human Parkinson’s disease (PD), scientists have developed strains of mice that overexpress alpha-synuclein. By studying a strain of mice bred to overexpress alpha-synuclein via the Thy-1 promoter, scientists have found these mice develop many of the age-related progressive motor symptoms of PD and demonstrate changes in sleep and anxiety.