• Toward an early diagnostic tool for Alzheimer's disease
    Despite all the research done on Alzheimer’s, there is still no early diagnostic tool for the disease. By looking at the brain wave components of individuals with the disease, scientists have identified a promising avenue of research that may not only help diagnose the disease, but also assess its severity.
  • Single gene change increases mouse lifespan by 20 percent
    By lowering the expression of a single gene, researchers have extended the average lifespan of a group of mice by about 20 percent — the equivalent of raising the average human lifespan by 16 years, from 79 to 95. The research team targeted a gene called mTOR, which is involved in metabolism and energy balance, and may be connected with the increased lifespan associated with caloric restriction.
  • Statins may slow human aging by protecting against telomere shortening: A feature of senescent cells
    Not only do statins extend lives by lowering cholesterol levels and reducing the risks of cardiovascular disease, but new research suggests that they may extend lifespans as well. Specifically, statins may reduce the rate at which telomeres shorten, a key factor in the natural aging process. This opens the door for using statins, or derivatives of statins, as an anti-aging therapy.
  • Newly discovered weakness in cancer cells make them more susceptible to chemotherapy
    A new weakness discovered in cancer cells may cause increased susceptibility to chemotherapy and other treatments. Researchers have identified the HDAC5 protein as essential for maintenance of telomeres within cancer cells that promote their longevity. Cells with longer telomeres are more resistant to therapies, while cells with shorter telomeres are more susceptible. By targeting this mechanism used to maintain telomeres, existing therapies could become more effective at eradicating cancer.