This article reviews the subject of Telomeres which have been recently found to have a great effect on cellular aging.
The largest supplier of a Telomere enhancing supplement is Isagenix, Inc. which sells Product B. Product B and the Isagenix multi level marketing approach are discussed thoroughly below with additional videos too.
It will take a while to review the entire article and videos but if you really want to know more about this exciting subject I recommend it:
(PS–I will be publishing a new book on Telomere research soon so look for an announcement on this blog site)
Your long term health and telomeres:
On this page we will cover the subject or telomeres, how they affect your long term health, and what can we do to improve our telomeres and therefore our long term health and longevity.
I’ve spent most of my life learning about Spiritual Growth and Natural Health, and wrote a book on longevity and physical immortality back in 2008 titled “Physical Immortality: A History and How to Guide”.
In the intervening five years I’ve met many more people involved in extreme longevity and learned a lot more. This led me to develop what I call “The 10 Principles of Personal Longevity”.
You can learn more about these principles by going to my website at https://personal-longevity.com or clicking on the graphic below:
Two of these principles are “The Science of Longevity” and “Keep your Physical Body Healthy”.
Both of these principles involve using new therapies and supplements which modern science & medicine, and ancient herbal practices say are good for our long term health.
One of the most exciting areas of scientific study on longevity has to do with the telomeres in our chromosomes, and how we can keep them long to extend our cell lives and therefore and long term health.
What are Telomeres?
First of all let’s learn what a telomere is and how it affects our cell’s life: (From Wikipedia)
A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. Its name is derived from the Greek nouns telos (τέλος) ‘end’ and merοs (μέρος, root: μερ-) ‘part.’ Telomere regions deter the degradation of genes near the ends of chromosomes by allowing chromosome ends to shorten, which necessarily occurs during chromosome replication Without telomeres, the genomes would progressively lose information and be truncated after cell division because the synthesis of Okazaki strands requires RNA primers attaching ahead on the lagging strand. Over time, due to each cell division, the telomere ends become shorter.
During cell division, enzymes that duplicate DNA cannot continue their duplication all the way to the end of chromosomes. If cells divided without telomeres, they would lose the ends of their chromosomes, and the necessary information they contain. The telomeres are disposable buffers blocking the ends of the chromosomes, are consumed during cell division, and are replenished by an enzyme, telomerase reverse transcriptase.
From the above information on Telomeres you can see that we need some way of increasing the length of our chromosome’s endings (the telomeres) for the cells to be able to keep living and dividing.
Next we will cover research on telomeres and related aging factors like oxidative stress.
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Research on Telomeres:
Diane Sawyer Story on Telomeres:
Below are some extracts from the article “ARE TELOMERES THE KEY TO AGING AND CANCER?”
Lots of work is being done on Telomere’s effects on aging and although there are other factors in aging telomeres seem to have a significant effect on aging. Some studies show that increasing the length of our telomeres alone can add 10-20 years to our lifespans:
What about telomeres and aging?
Geneticist Richard Cawthon and colleagues at the University of Utah found shorter telomeres are associated with shorter lives. Among people older than 60, those with shorter telomeres were three times more likely to die from heart disease and eight times more likely to die from infectious disease.
Dr. Richard Cawthon
While telomere shortening has been linked to the aging process, it is not yet known whether shorter telomeres are just a sign of aging – like gray hair – or actually contribute to aging.
If telomerase makes cancer cells immortal, could it prevent normal cells from aging? Could we extend lifespan by preserving or restoring the length of telomeres with telomerase? If so, does that raise a risk the telomerase also will cause cancer?
Scientists are not yet sure. But they have been able to use telomerase to make human cells keep dividing far beyond their normal limit in laboratory experiments, and the cells do not become cancerous……
How big a role do telomeres play in aging?
Some long-lived species like humans have telomeres that are much shorter than species like mice, which live only a few years. Nobody yet knows why. But it’s evidence that telomeres alone do not dictate lifespan.
Cawthon’s study found that when people are divided into two groups based on telomere lengths, the half with longer telomeres lives five years longer than those with shorter telomeres. That suggests lifespan could be increased five years by increasing the length of telomeres in people with shorter ones.
People with longer telomeres still experience telomere shortening as they age. How many years might be added to our lifespan by completely stopping telomere shortening? Cawthon believes 10 years and perhaps 30 years.
Some other related factors in aging:
A major cause of aging is “oxidative stress.” It is the damage to DNA, proteins and lipids (fatty substances) caused by oxidants, which are highly reactive substances containing oxygen. These oxidants are produced normally when we breathe, and also result from inflammation, infection and consumption of alcohol and cigarettes. In one study, scientists exposed worms to two substances that neutralize oxidants, and the worms’ lifespan increased an average 44 percent.
Another factor in aging is “glycation.” It happens when glucose sugar from what we eat binds to some of our DNA, proteins and lipids, leaving them unable to do their jobs. The problem becomes worse as we get older, causing body tissues to malfunction, resulting in disease and death. This may explain why studies in various laboratory animals indicate that restricting calorie intake extends lifespan.
It is possible oxidative stress, glycation, telomere shortening and chronological age – along with various genes – all work together to cause aging.
So we can see from the above research information that telomeres and oxidative stress can have a significant impact on longevity.
Next we will cover a variety of methods for increasing your telomere lengths and long term health.
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Methods of Improving Telomere lengths and increasing your life expectancy
Here is an article by Mary West on various actions you can take to increase your telomere lengths and therefore life expectancy:
1. Lead a healthful lifestyle.
In 2008, scientist evaluated the effect of a healthful lifestyle on telomerase levels. Telomerase is an enzyme that plays a vital role in the maintenance of telomeres. Without adequate levels of this enzyme, telomeres become progressively shorter.
The participants in the study were requested to make several lifestyle changes, including eating a diet plentiful in whole foods, fruits and vegetables but low in refined sugar and fat. Additionally they were to regularly engage in moderate workouts, breathing exercises and relaxation techniques. The healthful lifestyle caused the blood levels of telomerase to increase by 29 percent.
2. Consider calorie restriction.
This practice may lessen the natural telomere shortening process that occurs over the years, says Dr. Theodore S. Piliszek of King’s College School of Medicine of the University of London.
3. Enjoy a glass of non-alcoholic red wine daily.
A 2011 study showed resveratrol, a component of red wine, increased telomerase, which delayed the deterioration of cells. In addition, a 2012 study showed the compound increased the lifespan of mice. A daily glass on non-alcoholic red wine could be helpful.
4. Incorporate plenty of fish into your diet.
In 2010, a study published in JAMA found that individuals with the highest level of dietary omega-3s had the lowest rate of telomere shortening, while those with the least levels had the fastest rate of telomere shortening.
5. Eat dark chocolate.
Some studies suggest that the polyphenols contained in dark chocolate may slow telomere shortening.
6. Drink three cups of tea a day.
A Chinese study in 2009 found that those who drank three cups of tea per day had significantly longer telomeres than those who drank only a small amount. Green tea has a much higher percentage of valuable nutrients called polyphenols than black tea.
7. Abstain from smoking and alcohol consumption.
Shorter telomeres correlate with both of these practices.
8. Deal with stress.
Some research suggests stress accelerates the telomere shortening process. Practices such as massage, exercise and relaxation techniques can help siphon off anxiety.
It turns out that there are also some excellent supplements which can improve your telomere lengths too.
Now we will get to Isagenix Product B which is a telomerase increasing and antioxidant supplement.
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I’m ready to try out Product B and other Isagenix products!
Telomere Lengthening Products-Isagenix Product B
Dr. Mercola and Dr. Bill Andews on Telomeres:
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What should I know about Product B Antioxidants plus Telomere Support?
Product B positively supports telomere health by combining scientific breakthroughs in telomere support and the benefits of antioxidants in youthful aging. Product B helps maintain youthful function of cells and healthy telomeres so you can live a longer, healthier life.
How can I benefit from using Product B Antioxidants plus Telomere Support?
Product B’s full spectrum of natural bioactive antioxidants helps fight the effects of free radicals and oxidative stress, which can accelerate aging and contribute to poor health.
• Helps maintain youthful function of cells and healthy telomeres
• Helps protect the body from harmful free radicals that can accelerate aging and contribute to poor health
• Targets the sources of aging, such as oxidative stress
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The Composition of Product B
So what exactly is Product B composed of and how does it’s composition affect me?
Product B Ingredients – Supplement Facts
Serving Size: 2 capsules, Servings per Container: 60
Primary Ingredients: Vitamin C (ascorbic acid) 20 mg, 33% DV, Vitamin E (d-alpha tocopheryl succinate) 15 IU, 50% DV, Vitamin B12 (cyanocobalamin) 20 mcg, 333%, *DV (Percent Daily Values) are based on a 2,000 calorie diet
Proprietary Blend 910 mg – Milk thistle (Silybum marianum) seed extract, horny goat weed (Epimedium sagitatum) extract, grape (Vitis vinifera) seed extract, turmeric (Curcuma longa) root extract, ashwagandha (Withania somnifera) root extract, bacopa (Bacopa monnien) leaf extract, N-acety-L-cysteine, pomegranate (Punica granatum) fruit extract, DL-alpha lipoic acid, Asian genseng (Panax ginseng) root extract, berberine (Coptis chinensis) rhizome extract, bilberry (Vaccinium mrtillus) fruit extract, blueberry (Vaccinium angustifolium) fruit extract, red raspberry (Rubus idaeus) fruit extract, green tea extract, black tea (C. sinensis) leaf extract, acacia (Acacia nilotica) bark extract, plantain (Plantago major) leaf extract, L-gluthathione, velvet bean (mucuna pruiens) extract, hawthorn (Crataegus pinnatifida) root extract, quercetin, boswellis (Boswellis serrata) fruit extract, maca (Lepidum meyenii) root extract, hawthorn (C, pinnatifida) fruit extract, resveratrol, harada (Terminalia chebula) fruit extract, shilajit extract, chia (Salvia hispanica) seed extract.
Other Ingredients: Vegetable capsule, microcrystaline cellulose, magnesium stearate (vegetable source), silica.
About the Herbs in Product B:
Several Herbs are known by the ancients to provide anti aging benefits. One of these is Jinseng which is a component of Product B.
Also, Resveratrol (a red wine extract) has been shown to reduce cellular aging in independent studies. This component is included in Product B too.
Green Tea is included too and is also a known anti aging supplement and drink.
Antioxidants
There are also a variety of antioxidants in Product B such a: Vitamin C, and several antioxidant plant extracts.
Based on what we have learned earlier in this course it’s fair to say that Product B should have a lot of positive effects on cell aging and telomeres in you cells.
Another video on Product B which also talks about Product B Composition:
Next we will review some Product B testimonials.
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Product B Testimonials
There are quite a few people who swear by Product B and it’s effects on their bodies:
I began taking Product B in September 2010. The changes are both visible and invisible, but the biggest change is that I’ve lost all semblance of my age. If it weren’t for my driver’s license, I’d feel like I was 25. I have more energy, and every day I feel more and more alive. I went skiing with Associate Kirk M. and didn’t feel sore afterward.”
– Peter G
“After adding Product B to my regimen of using the Isagenix Pillars of Health [Cleanse for Life®, IsaLean® Shake, Ionix® Supreme and Ageless Essentials™ Daily Pack] friends have commented on how good I look! I feel I have increased energy and more stamina, too. I’m amazed at what I have noticed in such a short period of time. I love it!”
– Deborah K. Niagra Falls, New York
“I’ve been working with Isagenix Founder and Master Formulator John Anderson for nearly a year to help identify natural, non-drug substances that can help provide incremental support to our telomeres. Product B and the Isagenix Pillars of Health are the breakthrough support we’ve been looking for. ”
– Dr. William Andrews, Reno, Nevada
“My energy went through the roof. I recently went on a trip to Europe, and I didn’t feel sluggish with the time change. Every day keeps getting better and better.”
– Susan Sly
“I’ve always been energetic, but with Product B I’m running faster and further. I’m so fired up about this product!”
– Patty C
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Improve Your Telomeres and Make Money too
The Isagenix company uses multil level marketing to allow individuals to build a strong network of friends and affiliates to build additional income.
Some well known and multi billion dollar companies with stellar reputations also use multi level marketing to sell their products. These companies include:
• Avon Products
• Amway
• Primerica
• Sunrider International
…To name a few. Isagenix has been in business since 2002 selling a successful line of diet products and added Product B a few years ago.
When you become a client of the Isagenix products you can also become a marketer too.
The Compensation Plan:
Click here to download the Associate Compensation Plan Details
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