• In a surprise finding, gene mutation found linked to low-risk bladder cancer
    An international research team has discovered a genetic mutation linked to low-risk bladder cancer. The investigators identified STAG2 as one of the most commonly mutated genes in bladder cancer, particularly in tumors that do not spread. The finding suggests that checking the status of the gene may help identify patients who might do unusually well following cancer treatment.
  • Researchers sequence non-infiltrating bladder cancer exome
    Researchers have carried out the first exome sequencing for non-infiltrating bladder cancer, the most frequent type of bladder cancer and the one with the highest risk of recurrence. The results reveal new genetic pathways involved in the disease, such as cellular division and DNA repair, as well as new genes—not previously described—that might be crucial for understanding its origin and evolution.